Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438701 | 0.85 | CYP1A2 (0.48) | LTA4HCYP1A2CYP2C9CYP2C19SYK | |
| SCHEMBL7433296 | 0.85 | CACNA1B (0.32) | LTA4HCTSLPARP1CACNA1BMAPT | |
| SCHEMBL7431022 | 0.84 | CYP1A2 (0.47) | LTA4HCYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL7437714 | 0.82 | CYP1A2 (0.43) | LTA4HCYP1A2CYP2C9CYP2C19SLC7A5 | |
| SCHEMBL7443562 | 0.82 | CYP2C9 (0.36) | LTA4HCYP1A2CYP2C9CYP2C19SYK | |
| SCHEMBL7434047 | 0.82 | CYP1A2 (0.36) | LTA4HCYP1A2CYP2C9CYP2C19SYK | |
| SCHEMBL7439049 | 0.81 | CYP1A2 (0.36) | LTA4HCYP1A2CYP2C9CYP2C19SYK | |
| SCHEMBL7440427 | 0.81 | SMN1; SMN2 (0.44) | LTA4HCYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL7436644 | 0.80 | CYP1A2 (0.35) | LTA4HCYP1A2CYP2C9CYP2C19SYK | |
| SCHEMBL7442267 | 0.80 | SMN1; SMN2 (0.46) | LTA4HCYP1A2CYP2C9CYP2C19SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710153-A | INTERLEUKIN CONVERTING ENZYME INHIBITORS | ONO PHRAMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0761680-A2 | Tetrazole compounds having Interleukin-1beta converting enzyme inhibitory activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-03-12 | — | — | EP | disclosed |