Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | FDPS | P14324 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11257010 | 0.84 | TSHR (0.63) | TSHRBLMNPSR1FDPSACHE | |
| SCHEMBL11256995 | 0.84 | TSHR (0.63) | TSHRBLMNPSR1FDPSACHE | |
| SCHEMBL187138 | 0.83 | NPSR1 (0.75) | TSHRBLMNPSR1FDPSACHE | |
| SCHEMBL187137 | 0.83 | NPSR1 (0.75) | TSHRBLMNPSR1FDPSACHE | |
| SCHEMBL7437597 | 0.83 | HPGD (0.48) | FDPSACHEALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL7437591 | 0.83 | HPGD (0.48) | FDPSACHEALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL1766008 | 0.82 | FDPS (0.54) | NPSR1FDPSALDH1A1L3MBTL1PPARA | |
| SCHEMBL10007596 | 0.82 | FDPS (0.50) | FDPSALDH1A1L3MBTL1POLBKDM4E | |
| SCHEMBL7886610 | 0.81 | FDPS (0.52) | NPSR1FDPSACHEALDH1A1PPARA | |
| SCHEMBL5092331 | 0.78 | BLM (0.51) | TSHRBLMNPSR1FDPSACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070087-A | Aryl(alkyland alkylene)-N-((phenoxy and phenylthio)alkyl) aminoheterocyclics as cardiovascular, anthihistaminic, antisecretory and antiallergy agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1991-12-03 | — | — | US | disclosed |