Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429970 | 0.73 | — | — | |
| SCHEMBL7441100 | 0.69 | CRHR1 (0.34) | CRHR1 | |
| SCHEMBL6429914 | 0.68 | CRHR1 (0.45) | CRHR1 | |
| SCHEMBL5843381 | 0.68 | CRHR1 (0.34) | CRHR1 | |
| SCHEMBL5600404 | 0.67 | CRHR1 (0.53) | CRHR1 | |
| SCHEMBL5844782 | 0.65 | CRHR1 (0.30) | CRHR1 | |
| SCHEMBL7436842 | 0.64 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL5844241 | 0.64 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL7436852 | 0.63 | CRHR1 (0.33) | CRHR1 | |
| SCHEMBL5599806 | 0.62 | CRHR1 (0.33) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149583-A2 | Combinations of corticotropin releasing factor antagonists and growth hormone secretagogues | Pfizer Products Inc. (US) | 2001-10-31 | — | — | EP | claimed |