Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GRK2 | P25098 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7362026 | 0.84 | POLB (0.57) | MEN1KMT2ATSHRROCK2BCHE | |
| SCHEMBL658053 | 0.80 | LMNA (0.54) | MEN1KMT2ATSHRALDH1A1POLB | |
| SCHEMBL13589463 | 0.80 | MDM2 (0.48) | TSHRROCK2MDM2BCHEFDPS | |
| SCHEMBL11481061 | 0.79 | MDM2 (0.52) | MEN1KMT2AROCK2MDM2BCHE | |
| SCHEMBL7436948 | 0.79 | KDM4E (0.50) | KMT2AALDH1A1POLBRAB9AKDM4E | |
| SCHEMBL11650926 | 0.78 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1POLBCA12 | |
| SCHEMBL9780021 | 0.78 | KMT2A (0.57) | MEN1KMT2AALDH1A1POLBCA12 | |
| Benzene SCHEMBL28330086 | 0.78 | LMNA (0.53) | MEN1KMT2ATSHRALDH1A1POLB | |
| SCHEMBL1713162 | 0.78 | CA1 (0.51) | MEN1KMT2ATSHRALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL76327 | 0.78 | LMNA (0.53) | MEN1KMT2ATSHRALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |