Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29896347 | 0.98 | MEN1 (0.95) | MEN1CYP2C9KMT2AOPRM1DAO | |
| Methyl Alcohol SCHEMBL27817355 | 0.94 | MEN1 (0.88) | MEN1CYP2C9KMT2AOPRM1DAO | |
| SCHEMBL14679680 | 0.88 | MEN1 (0.78) | MEN1CYP2C9KMT2AOPRM1DAO | |
| SCHEMBL11569214 | 0.86 | MEN1 (0.76) | MEN1CYP2C9KMT2AOPRM1DAO | |
| SCHEMBL30144664 | 0.83 | MEN1 (0.70) | MEN1CYP2C9KMT2AOPRM1ALDH1A1 | |
| SCHEMBL31108372 | 0.83 | MEN1 (0.70) | MEN1CYP2C9KMT2AOPRM1ALDH1A1 | |
| SCHEMBL2256573 | 0.79 | OPRM1 (0.67) | MEN1CYP2C9KMT2AOPRM1DAO | |
| SCHEMBL2256575 | 0.79 | OPRM1 (0.67) | MEN1CYP2C9KMT2AOPRM1DAO | |
| SCHEMBL614021 | 0.77 | MEN1 (0.63) | MEN1CYP2C9KMT2A | |
| SCHEMBL12920581 | 0.77 | MEN1 (0.63) | MEN1CYP2C9KMT2AOPRM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170197919-A1 | 3-(Carboxyethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives | GRUENENTHAL GMBH (DE) | 2017-07-13 | — | — | US | disclosed |
| US-9487693-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2016-11-08 | — | — | US | disclosed |
| US-9487693-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2016-11-08 | — | — | US | disclosed |
| US-9487693-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2016-11-08 | — | — | US | disclosed |
| EP-2725017-B1 | CHROMENE COMPOUND | TOKUYAMA CORP (JP) | 2016-06-29 | — | — | EP | disclosed |
| US-20140154527-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| US-20140154527-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| US-20140154527-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| US-8729063-B2 | 3-aminopyrrolidine derivatives as modulators of chemokine receptors | INCYTE CORPORATION (US) | 2014-05-20 | — | — | US | disclosed |
| US-8729063-B2 | 3-aminopyrrolidine derivatives as modulators of chemokine receptors | INCYTE CORPORATION (US) | 2014-05-20 | — | — | US | disclosed |
| US-5053432-A | Antiprotozoa agents; treatment of malaria | BURROUGHS WELLCOME CO. (US) | 1991-10-01 | — | — | US | disclosed |
| EP-0445749-A1 | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |
| EP-0430771-A1 | Isoindolone derivatives, their preparation and their use as intermediates for the preparation of substance P antagonists | RHONE-POULENC SANTE (FR) | 1991-06-05 | — | — | EP | disclosed |
| US-4711896-A | ANTIDIABETIC, ANTILIPEMIC AGENTS | EPIS S.A. (CH) | 1987-12-08 | — | — | US | disclosed |
| US-4689344-A | ANTICHOLESTEROL AGENTS | EPIS S.A. (CH) | 1987-08-25 | — | — | US | disclosed |
| EP-0123238-B1 | NAPHTHOQUINONE DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1987-06-10 | — | — | EP | disclosed |
| EP-0185080-A1 | — | EPIS SA | 1986-06-25 | — | — | EP | disclosed |
| WO-1986000298-A1 | ALPHA-, OMEGA-DICARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND MEDICINES COMPOSED THEREOF | EPIS S.A. (CH) | 1986-01-16 | — | — | WO | disclosed |
| EP-0123238-A2 | Naphthoquinone derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-10-31 | — | — | EP | disclosed |
| US-4187152-A | Extractive distillation for separating ketones and/or alcohols from phenol and/or cresol | ALLIED CHEMICAL CORPORATION (US) | 1980-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170197919-A1 | 3-(Carboxyethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives | OPRK1, OPRD1, PKD1 | MEN1 2930/4885CYP2C9 1884/4885KMT2A 2071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.