Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6656374 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL20514279 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL11276948 | 0.84 | KMT2A (0.50) | ALDH1A1KMT2AMEN1LMNAPTGS1 | |
| SCHEMBL28847197 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL16811757 | 0.81 | CASP1 (0.49) | ALDH1A1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL10920938 | 0.81 | CASP1 (0.49) | ALDH1A1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL3048393 | 0.81 | KMT2A (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL28194047 | 0.81 | KMT2A (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL283103 | 0.80 | ALDH1A1 (0.48) | ALDH1A1CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL6302737 | 0.80 | ALDH1A1 (0.48) | ALDH1A1CYP1A2CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623120-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993014077-A1 | PIPERIDINEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |
| US-4723031-A | Processes for synthesizing substituted and unsubstituted aminoacetate esters | CHEVRON RESEARCH COMPANY (US) | 1988-02-02 | — | — | US | disclosed |
| US-4643762-A | Herbicidal 5-amino-3-oxo-4-(3-substituted-phenyl)-4-pyrroline and derivatives thereof | CHEVRON RESEARCH COMPANY (US) | 1987-02-17 | — | — | US | disclosed |