SCHEMBL283103

SCHEMBL283103

COC(=O)C(N)c1cccc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
AOC3 Q16853 1/20 0.44
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
GAA P10253 2/20 0.43
LMNA P02545 1/20 0.43
METAP2 P50579 3/20 0.42
METAP1 P53582 3/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6302737 1.00 ALDH1A1 (0.48) ALDH1A1KMT2AMEN1AOC3CYP1A2
Hydrochloric Acid SCHEMBL27633179 0.98 ALDH1A1 (0.47) ALDH1A1KMT2AMEN1AOC3CYP1A2
SCHEMBL13656748 0.90 KMT2A (0.41) ALDH1A1KMT2A
SCHEMBL283096 0.84 ALDH1A1 (0.50) ALDH1A1KMT2AAOC3NPC1RAB9A
SCHEMBL28157054 0.84 METAP2 (0.43) ALDH1A1KMT2AMEN1CYP1A2CYP2C9
SCHEMBL9664845 0.84 KMT2A (0.50) ALDH1A1KMT2ACYP1A2
SCHEMBL28847197 0.83 ALDH1A1 (0.47) ALDH1A1KMT2AMEN1AOC3CYP1A2
SCHEMBL27887663 0.83 ALDH1A1 (0.41) ALDH1A1KMT2AMEN1AOC3CYP1A2
SCHEMBL10920938 0.81 CASP1 (0.49) ALDH1A1KMT2AMEN1CYP1A2CYP2C9
SCHEMBL3048393 0.81 KMT2A (0.46) ALDH1A1KMT2AMEN1AOC3CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111315800-B Triazine ring-containing polymer and composition comprising same 日产化学株式会社 2022-05-31 CN disclosed
CN-107849425-B Solvent-free photocurable adhesive composition 日产化学工业株式会社 2021-09-21 CN disclosed
CN-107849392-B Film-forming composition for inkjet coating 日产化学工业株式会社 2021-07-13 CN disclosed
US-20210179779-A1 TRIAZINE-RING-CONTAINING POLYMER AND COMPOSITION INCLUDING SAME NISSAN CHEMICAL CORPORATION (JP) 2021-06-17 US disclosed
CN-108602953-B Triazine ring-containing polymer and film-forming composition containing the same 日产化学工业株式会社 2021-02-05 CN disclosed
CN-111315800-A Triazine ring-containing polymer and composition comprising same 日产化学株式会社 2020-06-19 CN disclosed
US-10619073-B2 Film-forming composition for ink-jet coating NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2020-04-14 US disclosed
US-10604681-B2 Solvent-free light-curable adhesive composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2020-03-31 US disclosed
US-10266701-B2 Composition for forming protective film for transparent conductive film NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-04-23 US disclosed
EP-2636704-B1 FILM-FORMING COMPOSITION NISSAN CHEMICAL CORP (JP) 2019-03-27 EP disclosed
US-20120049308-A1 TRIAZINE RING-CONTAINING POLYMER AND FILM-FORMING COMPOSITION COMPRISING SAME NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-03-01 US disclosed
EP-1593674-B1 OPTICALLY ACTIVE BISOXAZOLINE COMPOUNDS, PROCESS FOR PRODUCTION OF THE SAME AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2011-07-20 EP disclosed
US-7683215-B2 Optically active bisoxazoline compounds, process for production of the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-23 US disclosed
US-7671213-B2 Optically active bisoxazoline compounds, process for production of the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-7365223-B2 Method for selective targeting of apoptotic cells and small molecule ligands used thereof NST NEUROSURVIVAL TECHNOLOGIES LTD (IL) 2008-04-29 US disclosed
US-20080076941-A1 OPTICALLY ACTIVE BISOXAZOLINE COMPOUNDS, PROCESS FOR PRODUCTION OF THE SAME AND USE THEREOF ITAGAKI MAKOTO 2008-03-27 US disclosed
US-20080076931-A1 OPTICALLY ACTIVE BISOXAZOLINE COMPOUNDS, PROCESS FOR PRODUCTION OF THE SAME AND USE THEREOF ITAGAKI MAKOTO 2008-03-27 US disclosed
US-7288674-B2 Optically active bisoxazoline compounds, process for production of the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-30 US disclosed
US-20060149077-A1 Optically active bisoxazoline compounds, process for production of the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-07-06 US disclosed
EP-1593674-A1 OPTICALLY ACTIVE BISOXAZOLINE COMPOUNDS, PROCESS FOR PRODUCTION OF THE SAME AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2005-11-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060149077-A1 Optically active bisoxazoline compounds, process for production of the same and use thereof ACSL3, ADSL, SQLE ALDH1A1 897/4885KMT2A 4666/4885MEN1 3119/4885
US-20080076941-A1 OPTICALLY ACTIVE BISOXAZOLINE COMPOUNDS, PROCESS FOR PRODUCTION OF THE SAME AND USE THEREOF ACSL3, ADSL, SQLE ALDH1A1 897/4885KMT2A 4666/4885MEN1 3119/4885
US-20080076931-A1 OPTICALLY ACTIVE BISOXAZOLINE COMPOUNDS, PROCESS FOR PRODUCTION OF THE SAME AND USE THEREOF ACSL3, ADSL, SQLE ALDH1A1 897/4885KMT2A 4666/4885MEN1 3119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.