Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945581 | 0.84 | LMNA (0.44) | ALDH1A1LMNASMN1; SMN2CTRB1CA12 | |
| SCHEMBL5845871 | 0.82 | NR4A1 (0.51) | LMNASMN1; SMN2CTRB1CA12CA1 | |
| SCHEMBL5730701 | 0.81 | ALDH1A1 (0.45) | ALDH1A1LMNASMN1; SMN2CTRB1CA12 | |
| SCHEMBL2321117 | 0.80 | LMNA (0.56) | ALDH1A1LMNASMN1; SMN2CTRB1CA12 | |
| SCHEMBL234454 | 0.80 | LMNA (0.62) | ALDH1A1LMNASMN1; SMN2CTRB1CA12 | |
| SCHEMBL10942377 | 0.79 | LMNA (0.59) | LMNASMN1; SMN2CTRB1CA12CA1 | |
| SCHEMBL8407251 | 0.78 | SRD5A2 (0.48) | LMNASMN1; SMN2CTRB1TDP1KMT2A | |
| SCHEMBL23815127 | 0.78 | ALDH1A1 (0.54) | ALDH1A1LMNASMN1; SMN2CTRB1CA12 | |
| SCHEMBL23815128 | 0.78 | ALDH1A1 (0.54) | ALDH1A1LMNASMN1; SMN2CTRB1CA12 | |
| SCHEMBL7450597 | 0.78 | CTRB1 (0.49) | LMNASMN1; SMN2CTRB1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674623-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014776-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |