Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 19/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437255 | 1.00 | HTR3A (0.59) | HTR3AALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7502329 | 0.90 | HTR3A (0.70) | HTR3AALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7436272 | 0.87 | HTR3A (0.60) | HTR3AALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7436275 | 0.87 | HTR3A (0.60) | HTR3AALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7435708 | 0.86 | HTR3A (0.59) | HTR3AALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7435701 | 0.86 | HTR3A (0.59) | HTR3AALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7300091 | 0.81 | ALDH1A1 (0.83) | HTR3AALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL8714556 | 0.81 | ALDH1A1 (0.83) | HTR3AALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7281049 | 0.79 | HTR3A (0.57) | HTR3AALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL17163749 | 0.76 | HTR3A (0.92) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187166-A | Also useful as antipsychotic agents | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-02-16 | — | — | US | disclosed |
| EP-0469449-A1 | Azabicyclo derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-02-05 | — | — | EP | disclosed |