Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438625 | 0.87 | TRPA1 (0.44) | PPARAPPARGPPARDTRPA1GABRB1 | |
| SCHEMBL7438422 | 0.85 | TRPA1 (0.57) | PPARAPPARGPPARDTRPA1CTSK | |
| SCHEMBL8283003 | 0.85 | TRPA1 (0.57) | PPARAPPARGPPARDTRPA1CTSK | |
| SCHEMBL7441717 | 0.85 | TSHR (0.43) | — | |
| SCHEMBL29244798 | 0.84 | PPARA (0.50) | PPARAPPARGPPARDGABRB1GABRB2 | |
| SCHEMBL29244796 | 0.84 | PPARA (0.50) | PPARAPPARGPPARDGABRB1GABRB2 | |
| SCHEMBL7106002 | 0.80 | CTSK (0.47) | PPARAPPARGTRPA1CTSKCTSS | |
| SCHEMBL7106006 | 0.80 | CTSK (0.47) | PPARAPPARGTRPA1CTSKCTSS | |
| SCHEMBL23619006 | 0.79 | PPARA (0.48) | PPARAPPARGPPARDGABRB1GABRB2 | |
| SCHEMBL15432503 | 0.79 | PPARA (0.48) | PPARAPPARGPPARDGABRB1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |