Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PPID | Q08752 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1058808 | 1.00 | CTSK (0.41) | CTSKCTSSGAACYP1A2CYP2C9 | |
| SCHEMBL7431249 | 0.88 | GAA (0.40) | CTSKCTSSGAACYP1A2CYP2C9 | |
| SCHEMBL1058824 | 0.88 | GAA (0.40) | CTSKCTSSGAACYP1A2CYP2C9 | |
| SCHEMBL7432224 | 0.83 | PSENEN (0.43) | CTSKCTSSHTTPSENEN | |
| SCHEMBL30887573 | 0.83 | CTSS (0.42) | CTSKCTSSHTTPSENEN | |
| SCHEMBL29196423 | 0.83 | CTSS (0.42) | CTSKCTSSHTTPSENEN | |
| SCHEMBL7432219 | 0.83 | PSENEN (0.43) | CTSKCTSSHTTPSENEN | |
| SCHEMBL2909142 | 0.82 | ALDH1A1 (0.47) | GAACYP2C9CYP2C19MGAMSI | |
| SCHEMBL7432135 | 0.81 | GAA (0.42) | CTSKGAACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7432140 | 0.81 | GAA (0.42) | CTSKGAACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |