Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434947 | 0.88 | TAS1R3 (0.50) | TAS1R3TAS1R1MCHR1CTSKCTSB | |
| SCHEMBL7306059 | 0.87 | PSMB1 (0.40) | CTSBMMP3MMP9ALDH1A1PSMB5 | |
| SCHEMBL7306044 | 0.87 | PSMB1 (0.40) | CTSBMMP3MMP9ALDH1A1PSMB5 | |
| SCHEMBL7312702 | 0.85 | PSMB5 (0.42) | CTSBMMP3MMP9ALDH1A1PSMB5 | |
| SCHEMBL7312714 | 0.85 | PSMB5 (0.42) | CTSBMMP3MMP9ALDH1A1PSMB5 | |
| SCHEMBL7311345 | 0.84 | POLB (0.41) | CTSBMMP3MMP9ALDH1A1PSMB5 | |
| SCHEMBL7311337 | 0.84 | POLB (0.41) | CTSBMMP3MMP9ALDH1A1PSMB5 | |
| SCHEMBL8885998 | 0.84 | ALDH1A1 (0.34) | CTSBMMP3MMP9ALDH1A1PSMB5 | |
| SCHEMBL7300622 | 0.84 | POLB (0.37) | CTSKCTSBMMP3MMP9ALDH1A1 | |
| SCHEMBL7300609 | 0.84 | POLB (0.37) | CTSKCTSBMMP3MMP9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525420-B1 | Pseudopeptides and dipeptides characterised by a substituted methyl ketone moiety at the C-terminus as thiol protease inhibitors | MITSUBISHI CHEM CORP (JP) | 1999-05-12 | — | — | EP | disclosed |
| US-5834508-A | PROTEASE ENZYME INHIBITORS; MUSCLE DISORDERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| US-5639783-A | POTENT PROTEASE INHIBITOR FOR TREATING MUSCULAR, NERVOUS SYSTEM DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-06-17 | — | — | US | disclosed |