Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434177 | 0.85 | HSD11B1 (0.38) | HSD11B1TSHRALDH1A1LMNAHTT | |
| SCHEMBL7445423 | 0.84 | TSHR (0.41) | HSD11B1TSHRALDH1A1LMNAHTT | |
| SCHEMBL7432557 | 0.77 | ACE (0.40) | ALDH1A1GAA | |
| SCHEMBL7434337 | 0.76 | MMP1 (0.38) | ALDH1A1GAA | |
| SCHEMBL7435582 | 0.75 | ACE (0.40) | ALDH1A1GAA | |
| SCHEMBL7425886 | 0.75 | HSD11B1 (0.44) | HSD11B1TSHRALDH1A1LMNAHTT | |
| SCHEMBL7432526 | 0.74 | HSD11B1 (0.46) | HSD11B1TSHRALDH1A1LMNAHTT | |
| SCHEMBL7437645 | 0.69 | ACE (0.41) | HSD11B1TSHRALDH1A1GAACHRM1 | |
| SCHEMBL7438304 | 0.68 | ACE (0.40) | HSD11B1TSHRALDH1A1GAACHRM1 | |
| SCHEMBL7437087 | 0.67 | ACE (0.37) | ALDH1A1LMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |