Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.66 |
| ▸ | AHR | P35869 | 1/20 | 0.66 |
| ▸ | PLK1 | P53350 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220195 | 0.87 | ALDH1A1 (0.67) | SMN1; SMN2AHRPLK1ALDH1A1NPSR1 | |
| SCHEMBL10389855 | 0.86 | PLK1 (0.66) | SMN1; SMN2AHRPLK1ALDH1A1NPSR1 | |
| SCHEMBL7437950 | 0.79 | SMN1; SMN2 (0.69) | SMN1; SMN2AHRALDH1A1L3MBTL1MAPT | |
| SCHEMBL9393930 | 0.79 | PLK1 (0.64) | SMN1; SMN2AHRPLK1ALDH1A1NPSR1 | |
| SCHEMBL28120127 | 0.77 | PLK1 (0.62) | SMN1; SMN2AHRPLK1ALDH1A1MAPT | |
| SCHEMBL7433933 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2AHRALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL30100801 | 0.75 | MAPT (0.65) | SMN1; SMN2PLK1ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL11830538 | 0.74 | EYA3 (0.64) | SMN1; SMN2AHRALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL445085 | 0.74 | PLK1 (0.74) | SMN1; SMN2AHRPLK1ALDH1A1MAPT | |
| SCHEMBL8167484 | 0.73 | PTPN1 (0.56) | SMN1; SMN2AHRALDH1A1NPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551662-A1 | Benzofuranyl- and thiophenylmethylthio-alcanecarboxylic acid derivatives | BAYER AG (DE) | 1993-07-21 | — | — | EP | disclosed |