Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 5/20 | 0.59 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 9/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.35 |
| ▸ | MMP3 | P08254 | 3/20 | 0.35 |
| ▸ | MMP7 | P09237 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321930 | 1.00 | IL6ST (0.59) | IL6STSTAT3NAAAIDH1MMP2 | |
| SCHEMBL7321939 | 1.00 | IL6ST (0.59) | IL6STSTAT3NAAAIDH1MMP2 | |
| SCHEMBL2887707 | 0.87 | IL6ST (0.54) | IL6STSTAT3NAAAIDH1 | |
| SCHEMBL2887710 | 0.87 | IL6ST (0.54) | IL6STSTAT3NAAAIDH1 | |
| SCHEMBL9739729 | 0.85 | IL6ST (0.59) | IL6STSTAT3NAAAIDH1MMP2 | |
| SCHEMBL9739731 | 0.85 | IL6ST (0.59) | IL6STSTAT3NAAAIDH1MMP2 | |
| SCHEMBL17497683 | 0.83 | PPARA (0.44) | IL6STNAAAIDH1PPARA | |
| SCHEMBL9007609 | 0.83 | PPARA (0.44) | IL6STNAAAIDH1PPARA | |
| SCHEMBL19899198 | 0.83 | PPARA (0.44) | IL6STNAAAIDH1PPARA | |
| SCHEMBL19899230 | 0.83 | PPARA (0.44) | IL6STNAAAIDH1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364844-A | Hypotensive agents | SANKYO COMPANY, LIMITED (JP) | 1994-11-15 | — | — | US | disclosed |
| EP-0326364-A2 | Renin inhibitory oligopeptides, their preparation and use | Sankyo Company Limited (JP) | 1989-08-02 | — | — | EP | disclosed |