Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 5/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.40 |
| ▸ | IDH1 | O75874 | 4/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2887710 | 1.00 | IL6ST (0.54) | IL6STSTAT3FAAHIDH1NAAA | |
| SCHEMBL5523293 | 0.91 | IL6ST (0.53) | IL6STSTAT3FAAHIDH1NAAA | |
| SCHEMBL7321939 | 0.87 | IL6ST (0.59) | IL6STSTAT3IDH1NAAA | |
| SCHEMBL7321930 | 0.87 | IL6ST (0.59) | IL6STSTAT3IDH1NAAA | |
| SCHEMBL7438121 | 0.87 | IL6ST (0.59) | IL6STSTAT3IDH1NAAA | |
| SCHEMBL29866134 | 0.85 | PPARA (0.40) | IL6STFAAHIDH1NAAAMGLL | |
| SCHEMBL7359508 | 0.79 | IL6ST (0.55) | IL6STSTAT3FAAHIDH1NAAA | |
| SCHEMBL6432729 | 0.79 | IL6ST (0.50) | IL6STSTAT3IDH1NAAA | |
| SCHEMBL7359514 | 0.79 | IL6ST (0.55) | IL6STSTAT3FAAHIDH1NAAA | |
| SCHEMBL30984038 | 0.79 | IL6ST (0.56) | IL6STSTAT3FAAHIDH1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7855294-B2 | Cycloalkanopyridine derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-12-21 | — | — | US | disclosed |
| US-7855294-B2 | Cycloalkanopyridine derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-12-21 | — | — | US | disclosed |
| US-7855294-B2 | Cycloalkanopyridine derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-12-21 | — | — | US | disclosed |
| US-20070191419-A1 | Cycloalkanopyridine derivative | MSD K.K. (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20070191419-A1 | Cycloalkanopyridine derivative | MSD K.K. (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20070191419-A1 | Cycloalkanopyridine derivative | MSD K.K. (JP) | 2007-08-16 | — | — | US | disclosed |
| EP-1726590-A1 | CYCLOALKANOPYRIDINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-11-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191419-A1 | Cycloalkanopyridine derivative | OPRL1, OPRK1, AVPR2 | IL6ST 3137/4885STAT3 3295/4885FAAH 963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.