Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 6/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5460567 | 0.81 | CSNK1A1 (0.44) | ADRA2AADRA2BADRA2CCSNK1A1TYRO3 | |
| SCHEMBL29046781 | 0.77 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CFPR2ALDH1A1 | |
| SCHEMBL27693248 | 0.76 | FPR2 (0.44) | ADRA2AADRA2BADRA2CCSNK1A1TYRO3 | |
| SCHEMBL6448258 | 0.74 | FPR2 (0.43) | ADRA2AADRA2BADRA2CCSNK1A1TYRO3 | |
| SCHEMBL570524 | 0.74 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CCSNK1A1TYRO3 | |
| SCHEMBL28626525 | 0.74 | FPR2 (0.43) | ADRA2AADRA2BADRA2CCSNK1A1TYRO3 | |
| Bromide SCHEMBL28219788 | 0.73 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CCSNK1A1TYRO3 | |
| Hydrochloric Acid SCHEMBL28220351 | 0.73 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CCSNK1A1TYRO3 | |
| SCHEMBL4411652 | 0.73 | MMP1 (0.43) | ADRA2AADRA2BADRA2CCSNK1A1TYRO3 | |
| SCHEMBL23863035 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397365-B1 | Arylthiazolylimidazoles as 5HT3 Antagonists | PFIZER (US) | 1994-03-02 | — | — | EP | disclosed |
| US-4914207-A | ANTIEMETICS | PFIZER INC. (US) | 1990-04-03 | — | — | US | disclosed |