Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367331 | 0.87 | PPARG (0.45) | PPARAPPARGMMEACECYP1A2 | |
| SCHEMBL7367328 | 0.87 | PPARG (0.45) | PPARAPPARGMMEACECYP1A2 | |
| SCHEMBL8871963 | 0.84 | PPARG (0.48) | PPARAPPARGHPGDALDH1A1LMNA | |
| SCHEMBL9808996 | 0.80 | CYP1A2 (0.55) | PPARAMMEACECYP1A2CYP3A4 | |
| SCHEMBL6573900 | 0.80 | CYP1A2 (0.55) | PPARAMMEACECYP1A2CYP3A4 | |
| SCHEMBL6572920 | 0.80 | CYP1A2 (0.55) | PPARAMMEACECYP1A2CYP3A4 | |
| SCHEMBL9419783 | 0.80 | PPARG (0.49) | PPARAPPARGNR3C1HPGDALDH1A1 | |
| SCHEMBL9322510 | 0.79 | DPP4 (0.46) | PPARAPPARGMMEACEHPGD | |
| SCHEMBL9227082 | 0.76 | CYP1A2 (0.47) | PPARAPPARGMMEACECYP1A2 | |
| SCHEMBL7319197 | 0.75 | PPARA (0.48) | PPARAPPARGMMEACECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4929641-A | DIURETICS, ANGIOTENSIN CONVERTING ENZYMES | SCHERING CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |