Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367331 | 1.00 | PPARG (0.45) | PPARGPPARAMMEACEHPGD | |
| SCHEMBL7438291 | 0.87 | PPARA (0.40) | PPARGPPARAMMEACEHPGD | |
| SCHEMBL11259457 | 0.85 | HPGD (0.47) | PPARGPPARAHPGDALDH1A1CYP1A2 | |
| SCHEMBL6160470 | 0.84 | CPB2 (0.43) | PPARGPPARAMMEACEHPGD | |
| SCHEMBL7384644 | 0.84 | PPARG (0.57) | PPARGPPARAHPGDALDH1A1CYP1A2 | |
| SCHEMBL9227082 | 0.82 | CYP1A2 (0.47) | PPARGPPARAMMEACEHPGD | |
| SCHEMBL7318719 | 0.81 | CTNNB1 (0.50) | MMEACECYP1A2CYP2C19 | |
| SCHEMBL6154521 | 0.81 | CYP1A2 (0.63) | PPARAMMECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL838961 | 0.81 | CYP1A2 (0.63) | PPARAMMECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL838962 | 0.81 | CYP1A2 (0.63) | PPARAMMECYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563153-B1 | N-(MERCAPTOALKYL)AMIDES | SCHERING CORP (US) | 1995-03-15 | — | — | EP | disclosed |
| EP-0543892-B1 | N-(MERCAPTOALKYL)UREAS AND CARBAMATES | SCHERING CORP (US) | 1994-11-23 | — | — | EP | disclosed |
| US-5356925-A | For cardiovascular and urogenital disorders | SCHERING CORPORATION (US) | 1994-10-18 | — | — | US | disclosed |
| US-5262436-A | Administering; enzyme inhibitor | SCHERING CORPORATION (US) | 1993-11-16 | — | — | US | disclosed |
| EP-0563153-A1 | N-(MERCAPTOALKYL)AMIDES. | SCHERING CORP (US) | 1993-10-06 | — | — | EP | disclosed |
| US-5232920-A | For treating hypertension and congestive heart failure in mammals | SCHERING CORPORATION (US) | 1993-08-03 | — | — | US | disclosed |
| US-5219886-A | Cardiovascular disorders, analgesics, enzyme inhibitors | SCHERING CORPORATION (US) | 1993-06-15 | — | — | US | disclosed |
| EP-0543892-A1 | N-(MERCAPTOALKYL)UREAS AND CARBAMATES. | SCHERING CORP (US) | 1993-06-02 | — | — | EP | disclosed |
| EP-0393441-B1 | MERCAPTO-ACYLAMINO ACIDS | SCHERING CORPORATION (US) | 1993-05-26 | — | — | EP | disclosed |
| EP-0518943-A1 | MERCAPTOACYL AMINOLACTAM ENDOPEPTIDASE INHIBITORS | SCHERING CORPORATION (US) | 1992-12-23 | — | — | EP | disclosed |
| US-5173506-A | For treating hypertension, congestive heart failure, edema or urogenital disorders in mammals | SCHERING CORPORATION (US) | 1992-12-22 | — | — | US | disclosed |
| WO-1992011235-A1 | N-(MERCAPTOALKYL)AMIDES | SCHERING CORPORATION (US) | 1992-07-09 | — | — | WO | disclosed |
| WO-1992003410-A1 | N-(MERCAPTOALKYL)UREAS AND CARBAMATES | SCHERING CORPORATION (US) | 1992-03-05 | — | — | WO | disclosed |
| EP-0467957-A1 | MERCAPTO-ACYLAMINO ACIDS | SCHERING CORPORATION (US) | 1992-01-29 | — | — | EP | disclosed |
| US-5075302-A | Treating hypertension, congestive heart failure | SCHERING CORPORATION (US) | 1991-12-24 | — | — | US | disclosed |
| US-5061710-A | Atrial natriuretic factors | SCHERING CORPORATION (US) | 1991-10-29 | — | — | US | disclosed |
| WO-1991013870-A1 | MERCAPTOACYL AMINOLACTAM ENDOPEPTIDASE INHIBITORS | SCHERING CORPORATION (US) | 1991-09-19 | — | — | WO | disclosed |
| EP-0393441-A1 | Mercapto-acylamino acids | SCHERING CORPORATION (US) | 1990-10-24 | — | — | EP | disclosed |
| WO-1990012003-A1 | MERCAPTO-ACYLAMINO ACIDS | SCHERING CORPORATION (US) | 1990-10-18 | — | — | WO | disclosed |
| US-4929641-A | DIURETICS, ANGIOTENSIN CONVERTING ENZYMES | SCHERING CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |