Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9419783 | 0.91 | PPARG (0.49) | PPARGPPARAHPGDALDH1A1HTT | |
| SCHEMBL7438291 | 0.84 | PPARA (0.40) | PPARGPPARAHPGDALDH1A1HTT | |
| SCHEMBL7621562 | 0.83 | PPARG (0.47) | PPARGPPARAHPGDALDH1A1HTT | |
| SCHEMBL7384644 | 0.82 | PPARG (0.57) | PPARGPPARAHPGDALDH1A1HTT | |
| SCHEMBL6688791 | 0.78 | PPARG (0.49) | PPARGPPARAHPGDALDH1A1HTT | |
| SCHEMBL19502687 | 0.78 | ALDH1A1 (0.47) | PPARGPPARAALDH1A1EPHX2KMT2A | |
| SCHEMBL11983359 | 0.78 | PPARG (0.50) | PPARGPPARAHPGDALDH1A1HTT | |
| SCHEMBL27304316 | 0.78 | PPARG (0.50) | PPARGPPARAHPGDALDH1A1HTT | |
| SCHEMBL7273958 | 0.78 | PPARG (0.50) | PPARGPPARAHPGDALDH1A1HTT | |
| SCHEMBL9419792 | 0.78 | PPARG (0.64) | PPARGPPARAHPGDALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610177-A | Acylated amino acids as endothelin antagonists | WARNER-LAMBERT COMPANY (US) | 1997-03-11 | — | — | US | disclosed |