Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 4/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.48 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436219 | 0.93 | ALDH1A1 (0.55) | CASP1CAPN1CAPN2CTSKCTSS | |
| SCHEMBL25465074 | 0.79 | CTRB1 (0.57) | CTSKCTSSCTSLCTSBELANE | |
| SCHEMBL12442117 | 0.79 | CTRB1 (0.57) | CTSKCTSSCTSLCTSBELANE | |
| SCHEMBL5807162 | 0.77 | HPGD (0.52) | HPGDSMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL5057819 | 0.77 | HPGD (0.52) | HPGDSMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL14608990 | 0.74 | ELANE (0.57) | CTSKCTSSCTSLCTSBKMT2A | |
| SCHEMBL11405396 | 0.73 | HDAC1 (0.53) | HPGDSMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL11408765 | 0.72 | HPGD (0.49) | HPGDSMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL11415085 | 0.72 | SMN1; SMN2 (0.54) | HPGDSMN1; SMN2HDAC3HDAC1HDAC2 | |
| SCHEMBL5812588 | 0.72 | SMN1; SMN2 (0.54) | HPGDSMN1; SMN2HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |