Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27749642 | 0.79 | LMNA (0.34) | LMNANPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL1629951 | 0.78 | MIF (0.33) | LMNANPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL28792640 | 0.74 | MIF (0.32) | LMNAMIF | |
| SCHEMBL27749345 | 0.74 | MIF (0.36) | LMNANPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL167149 | 0.74 | — | — | |
| SCHEMBL4316216 | 0.73 | MGAM (0.36) | LMNATSHR | |
| SCHEMBL8428953 | 0.73 | DGAT1 (0.35) | CA1CA2CA7CA14 | |
| SCHEMBL28310176 | 0.73 | DPP4 (0.34) | LMNA | |
| SCHEMBL8719786 | 0.72 | — | — | |
| Ammonia Solution, Strong SCHEMBL3909004 | 0.72 | TSHR (0.48) | LMNANPC1TP53RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104449892-A | Methanol fuel additive and preparation method thereof | SHAANXI BAOJIANG NEW ENERGY TECHNOLOGY R & D CO LTD | 2015-03-25 | — | — | CN | disclosed |
| EP-0767661-A4 | AZAASPARTIC ACID ANALOGS AS INTERLEUKIN-1 BETA CONVERTING ENZYME INHIBITORS | SANOFI WINTHROP INC (US) | 1998-06-10 | — | — | EP | disclosed |
| EP-0767661-A1 | AZAASPARTIC ACID ANALOGS AS INTERLEUKIN-1 BETA CONVERTING ENZYME INHIBITORS | SANOFI WINTHROP, INC. (US) | 1997-04-16 | — | — | EP | disclosed |
| US-5565430-A | Azaaspartic acid analogs as interleukin-1β converting enzyme inhibitors | STERLING WINTHROP INC. (US) | 1996-10-15 | — | — | US | disclosed |
| WO-1996003982-A1 | AZAASPARTIC ACID ANALOGS AS INTERLEUKIN-1 BETA CONVERTING ENZYME INHIBITORS | SANOFI WINTHROP, INC. (US) | 1996-02-15 | — | — | WO | disclosed |