Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | YAP1 | P46937 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438627 | 0.87 | KMT2A (0.44) | KMT2AHTTNPC1RAB9ATSHR | |
| SCHEMBL7438619 | 0.87 | KMT2A (0.41) | ITGB3ITGA2BKMT2AHTTNPC1 | |
| SCHEMBL7443409 | 0.87 | ITGB3 (0.45) | ITGB3ITGA2BKMT2AHTTNPC1 | |
| SCHEMBL7498602 | 0.86 | ITGB3 (0.49) | ITGB3ITGA2BKMT2AHTTYAP1 | |
| SCHEMBL7445261 | 0.84 | L3MBTL1 (0.48) | ITGB3ITGA2BKMT2AYAP1NPC1 | |
| SCHEMBL7443415 | 0.83 | KMT2A (0.43) | KMT2AHTTNPC1RAB9ATSHR | |
| SCHEMBL7446996 | 0.82 | ITGB3 (0.45) | ITGB3ITGA2BKMT2AYAP1SSTR2 | |
| SCHEMBL7442054 | 0.82 | ITGB3 (0.46) | ITGB3ITGA2BKMT2AYAP1ALDH1A1 | |
| SCHEMBL7463085 | 0.78 | ITGB3 (0.44) | ITGB3ITGA2BKMT2ANPC1RAB9A | |
| SCHEMBL7446606 | 0.76 | STS (0.42) | ITGB3ITGA2BKMT2AYAP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384028-B1 | TREATMENT OF CARDIOVASCULAR DISORDERS, ANTICOAGULANTS AND VALVE REPLACEMENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| WO-1996029309-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-09-26 | — | — | WO | disclosed |