Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249295 | 0.86 | POLB (0.49) | PLK1ALDH1A1POLBGAALMNA | |
| SCHEMBL7486468 | 0.85 | TAAR1 (0.46) | CYP4F2CYP4A11ALDH1A1POLBGAA | |
| SCHEMBL10952675 | 0.82 | L3MBTL1 (0.50) | PLK1ALDH1A1POLBGAAFFAR1 | |
| SCHEMBL9779958 | 0.81 | SIRT2 (0.45) | CYP4F2CYP4A11GAAFFAR1THRB | |
| SCHEMBL6821960 | 0.81 | FFAR1 (0.52) | CYP4F2CYP4A11ALDH1A1POLBGAA | |
| SCHEMBL6818658 | 0.81 | SMN1; SMN2 (0.60) | ALDH1A1LMNAKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL5346268 | 0.81 | LOXL2 (0.53) | ALDH1A1POLBGAAKDM4EHPGD | |
| Sulfuric Acid SCHEMBL7322315 | 0.80 | CA12 (0.45) | CYP4F2CYP4A11ALDH1A1GAAFFAR1 | |
| SCHEMBL7151292 | 0.79 | POLB (0.49) | CYP4F2CYP4A11ALDH1A1POLBGAA | |
| SCHEMBL14279383 | 0.79 | LSS (0.46) | ALDH1A1POLBGAAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |