Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 4/20 | 0.57 |
| ▸ | PPARG | P37231 | 3/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | BCL2 | P10415 | 1/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.49 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | IL1RN | P18510 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438699 | 1.00 | YAP1 (0.57) | YAP1PPARGLTA4HMEN1ALDH1A1 | |
| SCHEMBL30823314 | 0.90 | PPARG (0.60) | YAP1PPARGLTA4HMEN1ALDH1A1 | |
| SCHEMBL27136481 | 0.90 | PPARG (0.60) | YAP1PPARGLTA4HMEN1ALDH1A1 | |
| SCHEMBL6440329 | 0.90 | ITGA4 (0.58) | MEN1ALDH1A1LMNAKMT2AITGA4 | |
| SCHEMBL4022466 | 0.90 | ITGA4 (0.58) | MEN1ALDH1A1LMNAKMT2AITGA4 | |
| SCHEMBL4022463 | 0.90 | ITGA4 (0.58) | MEN1ALDH1A1LMNAKMT2AITGA4 | |
| SCHEMBL7432421 | 0.87 | ITGA4 (0.50) | YAP1PPARGLTA4HALDH1A1LMNA | |
| SCHEMBL7432428 | 0.87 | ITGA4 (0.50) | YAP1PPARGLTA4HALDH1A1LMNA | |
| SCHEMBL6161729 | 0.84 | BCL2 (0.64) | YAP1PPARGLTA4HMEN1ALDH1A1 | |
| SCHEMBL3350988 | 0.84 | BCL2 (0.64) | YAP1PPARGLTA4HMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |