Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | AADAT | Q8N5Z0 | 4/20 | 0.39 |
| ▸ | GOT1 | P17174 | 1/20 | 0.39 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.39 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442234 | 0.83 | OPRM1 (0.51) | OPRM1OPRD1AADATGOT1KYAT1 | |
| SCHEMBL7441321 | 0.82 | THRB (0.40) | KMT2ATHRBKDM4EALDH1A1ALOX15 | |
| SCHEMBL7443268 | 0.76 | HRH4 (0.42) | OPRM1OPRD1AADATGOT1KYAT1 | |
| SCHEMBL7443272 | 0.76 | HRH4 (0.42) | OPRM1OPRD1AADATGOT1KYAT1 | |
| SCHEMBL7448178 | 0.73 | MME (0.50) | OPRM1OPRD1MMEACE | |
| SCHEMBL7163819 | 0.73 | MME (0.59) | OPRM1OPRD1AADATGOT1KYAT1 | |
| SCHEMBL7155964 | 0.69 | MAPT (0.60) | OPRM1OPRD1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL13916618 | 0.69 | USP2 (0.40) | OPRM1OPRD1THRBTSHRXIAP | |
| Hydrochloric Acid SCHEMBL11468168 | 0.67 | KMT2A (0.34) | OPRM1KMT2AALDH1A1TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL11468169 | 0.67 | KMT2A (0.34) | OPRM1KMT2AALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994026719-A1 | MERCAPTO-AMIDE DERIVATIVES USEFUL AS NEUTRAL ENDOPEPTIDASE AND ACE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-24 | — | — | WO | disclosed |