Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | AADAT | Q8N5Z0 | 6/20 | 0.46 |
| ▸ | GOT1 | P17174 | 1/20 | 0.46 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.46 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | SDCBP | O00560 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7163819 | 0.83 | MME (0.59) | OPRM1OPRD1AADATGOT1KYAT1 | |
| SCHEMBL7438781 | 0.83 | OPRM1 (0.45) | OPRM1OPRD1AADATGOT1KYAT1 | |
| SCHEMBL7155964 | 0.79 | MAPT (0.60) | OPRM1OPRD1MMEALDH1A1ALOX15 | |
| SCHEMBL8212856 | 0.78 | ALOX15 (0.43) | MMEKDM4EALDH1A1ALOX15TSHR | |
| SCHEMBL7501387 | 0.78 | ALOX15 (0.43) | MMEKDM4EALDH1A1ALOX15TSHR | |
| SCHEMBL5894080 | 0.78 | AADAT (0.56) | AADATGOT1KYAT1KYAT3ACE | |
| SCHEMBL12626584 | 0.72 | AADAT (0.51) | AADATGOT1KYAT1KYAT3ANPEP | |
| SCHEMBL4491852 | 0.72 | AADAT (0.51) | AADATGOT1KYAT1KYAT3ANPEP | |
| SCHEMBL2013546 | 0.72 | ALOX15 (0.66) | KDM4EALDH1A1ALOX15TSHRXIAP | |
| SCHEMBL30856522 | 0.72 | ALOX15 (0.66) | KDM4EALDH1A1ALOX15TSHRXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994026719-A1 | MERCAPTO-AMIDE DERIVATIVES USEFUL AS NEUTRAL ENDOPEPTIDASE AND ACE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-24 | — | — | WO | disclosed |