Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 18/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | PARL | Q9H300 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314021 | 0.75 | ELANE (0.70) | ELANE | |
| SCHEMBL7281982 | 0.74 | ELANE (0.56) | ELANE | |
| SCHEMBL7428497 | 0.69 | ELANE (0.81) | ELANE | |
| SCHEMBL9010433 | 0.68 | ELANE (0.74) | ELANE | |
| SCHEMBL8865749 | 0.68 | ELANE (0.73) | ELANE | |
| SCHEMBL7312226 | 0.67 | ELANE (1.00) | ELANE | |
| SCHEMBL7304376 | 0.66 | ELANE (0.64) | ELANE | |
| SCHEMBL7288412 | 0.64 | ELANE (1.00) | ELANE | |
| SCHEMBL7434313 | 0.64 | ELANE (1.00) | ELANE | |
| SCHEMBL8028141 | 0.62 | ALDH1A1 (0.72) | CACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512589-A | TREATING DEGENERATIVE DISEASES | STERLING WINTHROP INC. (US) | 1996-04-30 | — | — | US | claimed |
| EP-0483928-A1 | 2-Saccharinylmethyl aryl carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use | STERLING WINTHROP INC. (US) | 1992-05-06 | — | — | EP | claimed |