SCHEMBL8028141

SCHEMBL8028141

CC(C)COC(=O)c1cccc2ccccc12

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.72
TSHR P16473 1/20 0.72
ADRB2 P07550 2/20 0.67
ADRB1 P08588 2/20 0.67
ADRB3 P13945 2/20 0.67
CDC25B P30305 2/20 0.57
KDM4E B2RXH2 3/20 0.55
MAPT P10636 3/20 0.53
KMT2A Q03164 2/20 0.53
MEN1 O00255 1/20 0.53
TP53 P04637 1/20 0.53
NPY1R P25929 1/20 0.53
NPY2R P49146 1/20 0.53
ATM Q13315 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
HPGD P15428 2/20 0.53
HRH3 Q9Y5N1 1/20 0.51
CDC25A P30304 1/20 0.50
CDC25C P30307 1/20 0.50
CACNA1B Q00975 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28883856 0.88 ALDH1A1 (0.73) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL29268479 0.85 ADRB2 (0.64) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL27541872 0.84 ADRB2 (0.60) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL42787 0.84 ALDH1A1 (1.00) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL29387332 0.84 ALDH1A1 (1.00) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL8144263 0.84 ALDH1A1 (1.00) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL12019109 0.84 ADRB2 (0.59) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL14461611 0.83 ADRB2 (0.56) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL162635 0.83 ALDH1A1 (0.61) ALDH1A1TSHRADRB2ADRB1ADRB3
SCHEMBL6909094 0.83 ALDH1A1 (0.61) ALDH1A1TSHRADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111588514-B Method for preparing artificial cornea central part through photocatalysis 深圳华明生物科技有限公司 2023-03-31 CN claimed
CN-111320732-B Amphiphilic block copolymer with near-infrared thermal responsiveness and preparation and application thereof 苏州大学 2023-02-10 CN claimed
CN-113527642-B Polyester-based brush polymer electrolyte and preparation and application thereof 华中科技大学 2022-04-12 CN claimed
CN-106543306-A For the catalytic component of olefinic polymerization, catalyst and preparation method thereof 中国石油化工股份有限公司 2017-03-29 CN claimed
CN-106478845-A For the catalytic component of olefinic polymerization, catalyst and preparation method thereof 中国石油化工股份有限公司 2017-03-08 CN claimed
US-20240067651-A1 PRODRUGS OF MYELOPEROXIDASE INHIBITORS BIOHAVEN THERAPEUTICS LTD. 2024-02-29 US disclosed
US-20240067651-A1 PRODRUGS OF MYELOPEROXIDASE INHIBITORS BIOHAVEN THERAPEUTICS LTD. 2024-02-29 US disclosed
EP-3661900-B1 IRON-CATALYZED TRANSFER HYDROGENATION OF ESTERS TO ALCOHOLS EASTMAN CHEM CO (US) 2023-11-01 EP disclosed
CN-111588514-B Method for preparing artificial cornea central part through photocatalysis 深圳华明生物科技有限公司 2023-03-31 CN disclosed
CN-111320732-B Amphiphilic block copolymer with near-infrared thermal responsiveness and preparation and application thereof 苏州大学 2023-02-10 CN disclosed
US-11377580-B2 Methods for in situ formation of high glass transition temperature polymers SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2022-07-05 US disclosed
CN-113527642-B Polyester-based brush polymer electrolyte and preparation and application thereof 华中科技大学 2022-04-12 CN disclosed
EP-0173470-A2 Catalyst component for polymerization of olefins Tonen Corporation (JP) 1986-03-05 EP disclosed
EP-0171155-A1 Catalyst component for polymerization of olefins Tonen Corporation (JP) 1986-02-12 EP disclosed
EP-0171200-A2 Catalyst component for polymerization of olefins TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1986-02-12 EP disclosed
US-4565798-A COORDINATION CATALYSTS, TITANIUM, MAGNESIUM, SILICON COMPOUND TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1986-01-21 US disclosed
EP-0157472-A1 Process for polymerization of olefins TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1985-10-09 EP disclosed
EP-0156512-A1 Process for preparing catalyst component for polymerization of olefins TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1985-10-02 EP disclosed
EP-0147053-A1 A catalyst and a process for polymerization of olefins Tonen Corporation (JP) 1985-07-03 EP disclosed
EP-0145368-A2 Process for producing propylene block copolymers TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1985-06-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240067651-A1 PRODRUGS OF MYELOPEROXIDASE INHIBITORS MPO, CAT, SOD1 ALDH1A1 570/4885TSHR 2529/4885ADRB2 4561/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.