Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 6/20 | 0.54 |
| ▸ | CA2 | P00918 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1688815 | 0.88 | POLB (0.47) | ALDH1A1RAB9AHPGDNPC1AGTR1 | |
| SCHEMBL846596 | 0.86 | MAPT (0.44) | ALDH1A1RAB9AHPGDNPC1AGTR1 | |
| Hydrochloric Acid SCHEMBL1624734 | 0.83 | ALDH1A1 (0.64) | ALDH1A1RAB9AHPGDNPC1AGTR1 | |
| SCHEMBL9135725 | 0.83 | MAPT (0.53) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL7429994 | 0.82 | CASR (0.52) | ALDH1A1RAB9AHPGDNPC1AGTR1 | |
| SCHEMBL1039226 | 0.82 | MAPT (0.47) | ALDH1A1AGTR1MAPTMEN1KMT2A | |
| SCHEMBL5807704 | 0.81 | POLB (0.42) | ALDH1A1RAB9AHPGDNPC1AGTR1 | |
| SCHEMBL9135786 | 0.81 | MAPT (0.52) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL8299387 | 0.81 | FPR2 (0.47) | ALDH1A1RAB9AHPGDNPC1SMN1; SMN2 | |
| SCHEMBL18740367 | 0.81 | CTNNB1 (0.46) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | disclosed |