Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 13/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439443 | 0.89 | LTA4H (0.56) | KMT2ALTA4HCHEK2 | |
| SCHEMBL7445314 | 0.89 | LTA4H (0.56) | KMT2ALTA4HCHEK2 | |
| SCHEMBL7447210 | 0.88 | LTA4H (0.45) | KMT2ALTA4HCHEK2 | |
| SCHEMBL4965391 | 0.85 | LTA4H (0.64) | KMT2ALTA4HPOLB | |
| SCHEMBL7335832 | 0.83 | LTA4H (0.74) | LTA4HPOLB | |
| Hydrochloric Acid SCHEMBL7334091 | 0.82 | LTA4H (0.72) | KMT2ALTA4HPOLB | |
| SCHEMBL6610063 | 0.81 | LTA4H (0.57) | LTA4H | |
| SCHEMBL13809106 | 0.81 | LTA4H (0.76) | LTA4HPOLB | |
| SCHEMBL7326422 | 0.81 | LTA4H (0.76) | LTA4HPOLB | |
| SCHEMBL7327575 | 0.81 | LTA4H (0.60) | KMT2ALTA4HPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763021-A1 | PHENOXYALKYL SUBSTITUTED PIPERIDINES, PYRROLIDINES, MORPHOLINES AND TIOMORPHOLINES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1997-03-19 | — | — | EP | claimed |
| WO-1995033722-A1 | PHENOXYALKYL SUBSTITUTED PIPERIDINES, PYRROLIDINES, MORPHOLINES AND TIOMORPHOLINES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-12-14 | — | — | WO | claimed |
| EP-0763021-A1 | PHENOXYALKYL SUBSTITUTED PIPERIDINES, PYRROLIDINES, MORPHOLINES AND TIOMORPHOLINES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033722-A1 | PHENOXYALKYL SUBSTITUTED PIPERIDINES, PYRROLIDINES, MORPHOLINES AND TIOMORPHOLINES AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-12-14 | — | — | WO | disclosed |