Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | CTSG | P08311 | 2/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.36 |
| ▸ | CMA1 | P23946 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439007 | 0.83 | ELANE (0.41) | GSK3BLMNAALDH1A1L3MBTL1PRSS1 | |
| SCHEMBL7446353 | 0.82 | GSK3B (0.43) | GSK3BLMNAALDH1A1L3MBTL1CA1 | |
| SCHEMBL14750335 | 0.72 | BCHE (0.43) | LMNAALDH1A1L3MBTL1MAPTKMT2A | |
| SCHEMBL7439230 | 0.72 | GSK3B (0.46) | GSK3BLMNAALDH1A1L3MBTL1CA1 | |
| SCHEMBL1309694 | 0.71 | NPC1 (0.34) | LMNAL3MBTL1MAPTTP53KMT2A | |
| SCHEMBL9241143 | 0.67 | GRM1 (0.42) | GRM5GRM1PKM | |
| SCHEMBL28043144 | 0.67 | GSK3B (0.58) | GSK3BLMNAALDH1A1L3MBTL1CA1 | |
| SCHEMBL10275413 | 0.66 | GSK3B (0.61) | GSK3BALDH1A1CA1CA2PRSS1 | |
| Hydrochloric Acid SCHEMBL9241277 | 0.65 | GRM1 (0.41) | GRM5GRM1 | |
| SCHEMBL6413833 | 0.63 | CES2 (0.65) | GSK3BLMNAALDH1A1L3MBTL1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0849263-A2 | Pharmaceutical substituted propanoic acid derivatives | ELI LILLY AND COMPANY LIMITED (GB) | 1998-06-24 | — | — | EP | disclosed |