Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3342781 | 0.86 | CNR2 (0.48) | CNR2NPC1JAK2RAB9APAX8 | |
| SCHEMBL3141234 | 0.82 | MEN1 (0.50) | CNR2NPC1RAB9AALDH1A1GAA | |
| SCHEMBL2941860 | 0.82 | NPC1 (0.48) | CNR2NPC1JAK2RAB9APAX8 | |
| SCHEMBL11670765 | 0.82 | CNR2 (0.45) | CNR2NPC1JAK2RAB9APAX8 | |
| SCHEMBL13603918 | 0.82 | NPSR1 (0.44) | NPC1RAB9AALDH1A1POLBMEN1 | |
| SCHEMBL29951287 | 0.81 | ALDH1A1 (0.53) | CNR2ALDH1A1GAAKDM4EPOLB | |
| SCHEMBL6326806 | 0.81 | NPC1 (0.53) | CNR2NPC1JAK2RAB9APAX8 | |
| SCHEMBL4744062 | 0.80 | NPC1 (0.55) | CNR2NPC1JAK2RAB9APAX8 | |
| SCHEMBL10952007 | 0.80 | NPC1 (0.55) | CNR2NPC1JAK2RAB9APAX8 | |
| SCHEMBL10956818 | 0.80 | NPC1 (0.55) | CNR2NPC1JAK2RAB9APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998022494-A9 | METHODS AND COMPOUNDS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR SYNTHESIS | — | 1998-08-20 | — | — | WO | disclosed |