SCHEMBL29951287

SCHEMBL29951287

CCCCN(CC(N)=O)c1ccc(C=O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
ALDH3A1 P30838 3/20 0.53
ALDH1A3 P47895 3/20 0.53
MAPT P10636 3/20 0.43
KDM4E B2RXH2 2/20 0.43
GAA P10253 2/20 0.43
GLA P06280 1/20 0.43
HPGD P15428 1/20 0.43
GFER P55789 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
POLB P06746 1/20 0.42
EGFR P00533 1/20 0.40
ERBB2 P04626 1/20 0.40
CYP2A6 P11509 1/20 0.40
CYP2A13 Q16696 1/20 0.40
ATG4B Q9Y4P1 1/20 0.38
AR P10275 1/20 0.38
CNR2 P34972 2/20 0.37
CHRM2 P08172 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29952397 0.84 ALDH1A1 (0.57) ALDH1A1ALDH3A1ALDH1A3MAPTKDM4E
SCHEMBL420424 0.84 ALDH1A1 (0.68) ALDH1A1ALDH3A1ALDH1A3MAPTKDM4E
SCHEMBL10612062 0.82 ALDH1A1 (0.66) ALDH1A1ALDH3A1ALDH1A3MAPTKDM4E
SCHEMBL7439082 0.81 CNR2 (0.46) ALDH1A1MAPTKDM4EGAAGLA
SCHEMBL22562994 0.81 ALDH1A1 (0.63) ALDH1A1ALDH3A1ALDH1A3MAPTKDM4E
SCHEMBL26836706 0.81 ALDH1A1 (0.63) ALDH1A1ALDH3A1ALDH1A3MAPTKDM4E
SCHEMBL8626518 0.81 ALDH1A1 (0.63) ALDH1A1ALDH3A1ALDH1A3MAPTKDM4E
SCHEMBL29952977 0.80 ALDH1A1 (0.44) ALDH1A1ALDH3A1ALDH1A3KDM4EGAA
SCHEMBL29956977 0.80 SLC16A3 (0.40) ALDH1A1MAPTKDM4EGAAHPGD
SCHEMBL10010383 0.80 ALDH1A1 (0.61) ALDH1A1ALDH3A1ALDH1A3MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed