SCHEMBL7440462

SCHEMBL7440462

O=C(O)CN1C(=O)N(C(S)CCc2ccccc2)C(=O)C1C1CCCC1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACE P12821 10/20 0.45
MME P08473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7440453 0.80 MME (0.44) ACEMME
SCHEMBL7439237 0.80 ACE (0.41) ACE
SCHEMBL7443207 0.80 ACE (0.41) ACE
SCHEMBL7436241 0.79 ACE (0.42) ACE
SCHEMBL7435799 0.78 ACE (0.39) ACE
SCHEMBL7434091 0.78 ACE (0.41) ACE
SCHEMBL7445183 0.76 ACE (0.38) ACE
SCHEMBL7433475 0.75 SIGMAR1 (0.44) ACEMME
SCHEMBL7437652 0.74 KMT2A (0.40) ACE
SCHEMBL7428792 0.73 CYP2D6 (0.45) ACEMME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0640594-A1 Hydantoin derivative as metalloprotease inhibitor FUJIREBIO INC. (JP) 1995-03-01 EP disclosed