Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | HTR1D | P28221 | 3/20 | 0.38 |
| ▸ | HTR1F | P30939 | 3/20 | 0.38 |
| ▸ | HTR1B | P28222 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7392449 | 0.93 | RAB9A (0.42) | CTSSITGB3ITGA2BRAB9ANPC1 | |
| SCHEMBL7443324 | 0.92 | NPC1 (0.41) | CTSSITGB3ITGA2BRAB9ANPC1 | |
| SCHEMBL7431007 | 0.92 | ITGB3 (0.41) | CTSSITGB3ITGA2BRAB9ANPC1 | |
| SCHEMBL7392148 | 0.91 | ITGB3 (0.38) | CTSSITGB3ITGA2BRAB9ANPC1 | |
| SCHEMBL7390246 | 0.91 | ITGB3 (0.46) | ITGB3ITGA2BRAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7391203 | 0.91 | ITGB3 (0.41) | CTSSITGB3ITGA2BRAB9ANPC1 | |
| SCHEMBL7443951 | 0.89 | ITGB3 (0.40) | CTSSITGB3ITGA2BRAB9ANPC1 | |
| SCHEMBL7394106 | 0.87 | RAB9A (0.41) | ITGB3ITGA2BRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7434120 | 0.87 | DRD3 (0.41) | ITGB3ITGA2BRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7432983 | 0.87 | NPC1 (0.41) | ITGB3ITGA2BRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760364-B1 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI CHEMICALS INC (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-0760364-A2 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-03-05 | — | — | EP | disclosed |