Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1F | P30939 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398724 | 0.94 | ITGB3 (0.38) | ITGB3ITGA2BTRPV1NPC1LMNA | |
| SCHEMBL7392449 | 0.92 | RAB9A (0.42) | ITGB3ITGA2BTRPV1CTSSNPC1 | |
| SCHEMBL7394889 | 0.92 | ITGB3 (0.37) | ITGB3ITGA2BTRPV1NPC1LMNA | |
| SCHEMBL7390234 | 0.91 | ITGB3 (0.40) | ITGB3ITGA2BTRPV1NPC1LMNA | |
| SCHEMBL7439409 | 0.91 | CTSS (0.40) | ITGB3ITGA2BCTSSNPC1LMNA | |
| Hydrochloric Acid SCHEMBL7395647 | 0.91 | ITGB3 (0.40) | ITGB3ITGA2BTRPV1NPC1LMNA | |
| SCHEMBL7390246 | 0.91 | ITGB3 (0.46) | ITGB3ITGA2BTRPV1NPC1LMNA | |
| SCHEMBL7391195 | 0.89 | ITGB3 (0.39) | ITGB3ITGA2BTRPV1CTSSNPC1 | |
| SCHEMBL7386945 | 0.86 | DRD3 (0.38) | ITGB3ITGA2BTRPV1NPC1LMNA | |
| SCHEMBL7394106 | 0.86 | RAB9A (0.41) | ITGB3ITGA2BNPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760364-B1 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI CHEMICALS INC (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-0760364-A2 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-03-05 | — | — | EP | disclosed |