Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 5/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13805607 | 0.67 | TRPA1 (0.36) | TRPA1 | |
| SCHEMBL819265 | 0.67 | — | — | |
| SCHEMBL19629537 | 0.65 | CYP2A6 (0.38) | ALDH1A1LMNACYP3A4 | |
| SCHEMBL224492 | 0.64 | NOS3 (0.42) | NOS3NOS1NOS2TRPA1ACHE | |
| SCHEMBL60763 | 0.64 | — | — | |
| SCHEMBL452182 | 0.64 | — | — | |
| SCHEMBL29861109 | 0.64 | — | — | |
| SCHEMBL876180 | 0.64 | TSHR (0.33) | — | |
| SCHEMBL16759 | 0.62 | MAOA (0.34) | NOS3NOS1NOS2TRPA1ALDH1A1 | |
| SCHEMBL789571 | 0.62 | NOS3 (0.32) | NOS3NOS1NOS2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462884-B1 | TRH DERIVATIVES, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1993-06-16 | — | — | EP | claimed |
| EP-0462884-B1 | TRH DERIVATIVES, THEIR PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1993-06-16 | — | — | EP | disclosed |