Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 8/20 | 0.63 |
| ▸ | MMP3 | P08254 | 8/20 | 0.63 |
| ▸ | MMP7 | P09237 | 2/20 | 0.57 |
| ▸ | MMP9 | P14780 | 2/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408812 | 0.83 | MMP1 (0.79) | MMP1MMP3MMP7MMP9MMP2 | |
| SCHEMBL7409487 | 0.83 | MMP1 (0.79) | MMP1MMP3MMP7MMP9MMP2 | |
| SCHEMBL7450397 | 0.77 | MMP1 (0.73) | MMP1MMP3MMP7MMP9MMP2 | |
| SCHEMBL7404455 | 0.77 | MMP1 (0.73) | MMP1MMP3MMP7MMP9MMP2 | |
| SCHEMBL7404453 | 0.77 | MMP1 (0.73) | MMP1MMP3MMP7MMP9MMP2 | |
| SCHEMBL9329102 | 0.76 | MMP1 (0.52) | MMP1MMP3MMP7MMP9MMP2 | |
| SCHEMBL3039559 | 0.75 | NR4A2 (0.55) | MMP1MMP3MMP7MMP9MMP2 | |
| SCHEMBL7372235 | 0.75 | NR4A2 (0.55) | MMP1MMP3MMP7MMP9MMP2 | |
| Hydrochloric Acid SCHEMBL3046435 | 0.74 | NR4A2 (0.54) | MMP1MMP3MMP7MMP9MMP2 | |
| SCHEMBL3463311 | 0.73 | MEN1 (0.53) | MMP1MMP3MMP7MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925303-A1 | PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998008853-A1 | PHOSPHINIC ACID AMIDES AS MATRIX METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |