Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.60 |
| ▸ | LTA4H | P09960 | 3/20 | 0.55 |
| ▸ | EBP | Q15125 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446083 | 0.90 | F2 (0.60) | F2LTA4HHRH3KCNH2 | |
| SCHEMBL7446154 | 0.87 | F2 (0.70) | F2LTA4HESR1ESR2 | |
| SCHEMBL7964914 | 0.87 | F2 (0.58) | F2LTA4HHRH3ESR1KCNH2 | |
| SCHEMBL9400262 | 0.84 | LTA4H (0.65) | LTA4HEBPSIGMAR1HRH3ESR1 | |
| SCHEMBL9400242 | 0.84 | LTA4H (0.61) | LTA4HEBPSIGMAR1ESR1ESR2 | |
| SCHEMBL8932364 | 0.83 | LTA4H (0.63) | LTA4HEBPSIGMAR1HRH3ESR1 | |
| SCHEMBL7440123 | 0.83 | LTA4H (0.62) | F2LTA4HHRH3ESR1PSMB1 | |
| SCHEMBL7452240 | 0.82 | F2 (0.56) | F2LTA4HEBPSIGMAR1HRH3 | |
| SCHEMBL7446550 | 0.82 | F2 (0.64) | F2HRH3ESR1ESR2 | |
| SCHEMBL227235 | 0.82 | LTA4H (0.61) | LTA4HEBPSIGMAR1HRH3ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |