Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.63 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.55 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.55 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 6/20 | 0.52 |
| ▸ | EBP | Q15125 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9400262 | 0.99 | LTA4H (0.65) | LTA4HPSMB1PSMB5PSMB2PTGS2 | |
| SCHEMBL229153 | 0.88 | LTA4H (0.61) | LTA4HPSMB1PSMB5PSMB2ESR1 | |
| SCHEMBL227235 | 0.88 | LTA4H (0.61) | LTA4HPSMB1PSMB5PSMB2ESR1 | |
| SCHEMBL9400242 | 0.88 | LTA4H (0.61) | LTA4HPSMB1PSMB5PSMB2ESR1 | |
| SCHEMBL7440123 | 0.83 | LTA4H (0.62) | LTA4HPSMB1PSMB5PSMB2ESR1 | |
| SCHEMBL7439644 | 0.83 | F2 (0.60) | LTA4HPSMB1PSMB5PSMB2ESR1 | |
| SCHEMBL7349591 | 0.81 | LTA4H (0.70) | LTA4HPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL7134872 | 0.79 | LTA4H (1.00) | LTA4HPSMB1PSMB5PSMB2PTGS2 | |
| SCHEMBL7442242 | 0.79 | LTA4H (0.69) | LTA4HPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL228892 | 0.78 | LTA4H (0.69) | LTA4HPSMB1PSMB5PSMB2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996026935-A1 | 2-BENZYL-3-ARYLBENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 1996-09-06 | — | — | WO | disclosed |