⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442692 | 0.90 | KMT2A (0.32) | — | |
| SCHEMBL7442264 | 0.87 | KDM4E (0.36) | — | |
| SCHEMBL9038396 | 0.86 | PTPN1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL7317155 | 0.85 | PTPN1 (0.36) | — | |
| SCHEMBL7442764 | 0.82 | GAA (0.39) | — | |
| SCHEMBL7310836 | 0.77 | ACHE (0.43) | — | |
| Hydrochloric Acid SCHEMBL7310685 | 0.76 | ACHE (0.42) | — | |
| SCHEMBL9802613 | 0.75 | NPC1 (0.32) | — | |
| SCHEMBL9802336 | 0.75 | KDM4E (0.43) | — | |
| Hydrochloric Acid SCHEMBL9802239 | 0.73 | MAPT (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162929-A | Process for the manufacture of bisphosphine oxide and bisphosphonate compounds | HOFFMANN-LA ROCHE INC. (US) | 2000-12-19 | — | — | US | claimed |
| US-6156756-A | Triazolo [4,5-d]pyrimidine compounds, their use as medicaments, compositions containing them and processes for their preparation | ASTRAZENECA UK LIMITED (GB) | 2000-12-05 | — | — | US | claimed |
| US-6110928-A | HUMAN OR VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 2000-08-29 | — | — | US | claimed |
| US-6103698-A | USEFUL IN TREATING CANCER IN A MAMMAL; IN COMBINATION WITH PACLITAXEL AND TAXOTERE | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-15 | — | — | US | claimed |
| US-6080878-A | Method of preparing 16-dehydro vitamin D compounds | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 2000-06-27 | — | — | US | claimed |
| US-6075034-A | Spiro[piperidine-4,1'-pyrrolo [3,4-C] pyrrole]derivatives | HOFFMANN-LA ROCHE INC. (US) | 2000-06-13 | — | — | US | claimed |
| US-6022868-A | TREATING DISEASES IN THE CENTRAL NERVOUS SYSTEM RELATED TO MALFUNCTIONING OF THE NICOTINIC CHOLINERGIC SYSTEM. | NOVO NORDISK ALS (DK) | 2000-02-08 | — | — | US | claimed |
| US-6020504-A | Process for the preparation of chroman derivatives | LONZA AG (CH) | 2000-02-01 | — | — | US | claimed |
| US-6015790-A | Methods and compositions for treating rheumatoid arthritis | BASF AKTIENGESELLSCHAFT (DE) | 2000-01-18 | — | — | US | claimed |
| US-5994569-A | USEFUL IN THE TREATMENT OR PREVENTION OF VITAMIN D DEPENDENT DISORDERS AND OF IL-12-DEPENDENT AUTOIMMUNE DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1999-11-30 | — | — | US | claimed |
| US-4605656-A | Pyridine and pyrazine oxime compounds as fungicides | HOFFMANN-LA ROCHE INC. (US) | 1986-08-12 | — | — | US | claimed |
| US-4584295-A | Pyrimidylmethyl thiophosphorus esters useful for the control of insects, mites and nematodes | HOFFMANN-LA ROCHE INC. (US) | 1986-04-22 | — | — | US | claimed |
| US-4562185-A | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-31 | — | — | US | claimed |
| US-4549022-A | ANTIBACTERIAL AGENT; STIMULANT ON CENTRAL NERVOUS SYSTEM | HOFFMANN-LA ROCHE INC. (US) | 1985-10-22 | — | — | US | claimed |
| US-4434171-A | NEUROLEPTIC, ANTIDEPRESSANT | SANDOZ LTD. (CH) | 1984-02-28 | — | — | US | claimed |
| US-4369186-A | INSECTICIDE, MITICIDE, FUNGICIDE, AND HERBICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1983-01-18 | — | — | US | claimed |
| US-4363809-A | BENZOMORPHAN DERIVATIVE INHIBITING LUTEINIZING HOROME SECRETION | SANDOZ LTD. (CH) | 1982-12-14 | — | — | US | claimed |
| US-4360525-A | NEUROLEPTIC AGENTS, ANTIDEPRESSANTS, SLEEP PROMOTERS | SANDOZ LTD. (CH) | 1982-11-23 | — | — | US | claimed |
| US-4335134-A | INSECTICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-06-15 | — | — | US | claimed |
| US-4112112-A | Pyrrolo[2,1-b] [3]benzazepines useful for producing a skeletal muscle relaxing or tranquilizing effect | MERCK & CO., INC. (US) | 1978-09-05 | — | — | US | claimed |