Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442692 | 0.88 | KMT2A (0.32) | — | |
| SCHEMBL9038396 | 0.88 | PTPN1 (0.37) | KDM4EHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL7317155 | 0.87 | PTPN1 (0.36) | KDM4EHPGDHSD17B10 | |
| SCHEMBL7439893 | 0.87 | — | — | |
| SCHEMBL7442764 | 0.84 | GAA (0.39) | KDM4E | |
| Hydrochloric Acid SCHEMBL7493249 | 0.84 | KMT2A (0.35) | HSD17B10 | |
| SCHEMBL8829352 | 0.83 | NCEH1 (0.40) | KDM4E | |
| SCHEMBL7310836 | 0.82 | ACHE (0.43) | KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL7310685 | 0.81 | ACHE (0.42) | KDM4EHPGD | |
| SCHEMBL7443351 | 0.79 | ADORA3 (0.36) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5621133-A | PREPARING A 1-(3,4-DIALKOXYPHENYL),3-HYDROXYALKANE(C6-C12) BY EPOXIDIZING A HALO DERIVATIVE WITH A BASE FOLLOWED BY DECYCLICIZING WITH AN ORGANOMETALLIC COMPOUND IN A SOLVENT; NAPHTHYLENES, ISOCHROMENES AND ISOTHIOCHROMENES | DENINNO MICHAEL P (US) | 1997-04-15 | — | — | US | disclosed |
| US-5591884-A | PROTECTED HYDROXYALKYLCATECHOL INTERMEDIATES | ABBOTT LABORATORIES (US) | 1997-01-07 | — | — | US | disclosed |
| WO-1996038435-A1 | DOPAMINE AGONISTS | ABBOTT LABORATORIES (US) | 1996-12-05 | — | — | WO | disclosed |