Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446241 | 0.86 | DRD4 (0.40) | OPRM1MAPTMEN1KMT2ASCN4A | |
| SCHEMBL7282057 | 0.84 | SCN4A (0.42) | OPRM1MAPTL3MBTL1OPRL1SCN4A | |
| SCHEMBL10837562 | 0.74 | HTR7 (0.45) | MAPTMEN1KMT2ASCN4AALDH1A1 | |
| SCHEMBL7431862 | 0.74 | TP53 (0.56) | MAPTL3MBTL1MEN1KMT2AACHE | |
| SCHEMBL11929283 | 0.73 | SCN4A (0.43) | MAPTMEN1KMT2ASCN4AALDH1A1 | |
| SCHEMBL22407742 | 0.71 | HTT (0.44) | MAPTMEN1KMT2ASCN4AALDH1A1 | |
| SCHEMBL7289343 | 0.71 | ALDH1A1 (0.42) | MEN1KMT2ASCN4AALDH1A1TSHR | |
| SCHEMBL7279257 | 0.71 | CYP3A4 (0.60) | OPRM1MAPTMEN1KMT2AACHE | |
| SCHEMBL11929144 | 0.70 | HTT (0.47) | MEN1KMT2ASCN4AALDH1A1TSHR | |
| SCHEMBL7288792 | 0.69 | ADRB1 (0.45) | MAPTSCN4AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |