Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL227416 | 1.00 | EPHX1 (0.61) | EPHX1HPGDKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3453982 | 0.98 | SMN1; SMN2 (0.61) | EPHX1HPGDKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4303783 | 0.93 | — | — | |
| SCHEMBL224441 | 0.88 | — | — | |
| SCHEMBL10824411 | 0.84 | ALDH1A1 (0.60) | EPHX1SMN1; SMN2ALDH1A1NPSR1NPC1 | |
| SCHEMBL3075216 | 0.83 | EPHX1 (0.68) | EPHX1HPGDKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9639138 | 0.83 | SMN1; SMN2 (0.67) | EPHX1HPGDKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10587847 | 0.81 | ALDH1A1 (0.83) | EPHX1HPGDKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL943151 | 0.80 | EPHX2 (0.58) | EPHX1HPGDKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL854700 | 0.80 | MTNR1A (0.45) | EPHX1HPGDKMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |