Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | REN | P00797 | 16/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | CTSE | P14091 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430523 | 0.92 | CTSS (0.52) | CTSSCTSKRENHDAC4HDAC1 | |
| SCHEMBL9833907 | 0.89 | CTSS (0.51) | CTSSCTSKRENHDAC4HDAC1 | |
| SCHEMBL7284721 | 0.88 | CTSS (0.55) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL7437469 | 0.88 | CTSS (0.50) | CTSSCTSKRENHDAC4HDAC1 | |
| SCHEMBL7274022 | 0.88 | CTSS (0.50) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL9358862 | 0.88 | CTSS (0.50) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL7274017 | 0.88 | CTSS (0.50) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL7272375 | 0.86 | CTSS (0.53) | CTSSCTSKRENHDAC4HDAC1 | |
| SCHEMBL3606570 | 0.86 | CTSS (0.53) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL8225301 | 0.86 | CTSS (0.53) | CTSSCTSKRENHDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826815-A | HYPOTENSIVE | ABBOTT LABORATORIES (US) | 1989-05-02 | — | — | US | disclosed |
| US-4652551-A | PEPTIDE, HYPOTENSIVE | ABBOTT LABORATORIES (US) | 1987-03-24 | — | — | US | disclosed |