Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | REN | P00797 | 16/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | CTSE | P14091 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430523 | 0.91 | CTSS (0.52) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL7272375 | 0.90 | CTSS (0.53) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL5709619 | 0.90 | CTSS (0.53) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL13306504 | 0.90 | CTSS (0.53) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL7284721 | 0.89 | CTSS (0.55) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL7437469 | 0.89 | CTSS (0.50) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL7274017 | 0.89 | CTSS (0.50) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL9358862 | 0.89 | CTSS (0.50) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL7440374 | 0.89 | CTSS (0.50) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL7274022 | 0.89 | CTSS (0.50) | CTSSCTSKRENCTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258289-A4 | PEPTIDE ANALOGS | — | 1991-01-02 | — | — | EP | disclosed |
| US-4857507-A | HYPOTENSIVE AGENT | ABBOTT LABORATORIES (US) | 1989-08-15 | — | — | US | disclosed |
| US-4855286-A | HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-08 | — | — | US | disclosed |
| EP-0258289-A1 | PEPTIDE ANALOGS | ABBOTT LABORATORIES (US) | 1988-03-09 | — | — | EP | disclosed |
| EP-0255082-A2 | Renin-inhibiting di- and tripeptides, methods for their production, drugs containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-02-03 | — | — | EP | disclosed |
| WO-1987004349-A1 | PEPTIDE ANALOGS | DELLARIA JOSEPH | 1987-07-30 | — | — | WO | disclosed |