Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | BCL9 | O00512 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1714950 | 0.86 | HTR2A (0.70) | HTR2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL733740 | 0.83 | ALDH1A1 (0.44) | ALDH1A1LMNACYP2C19HTTMAOB | |
| SCHEMBL20564407 | 0.83 | IDO1 (0.62) | HTR2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6322393 | 0.80 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1LMNAMGLLBCL9 | |
| SCHEMBL20377184 | 0.80 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1LMNAMGLLBCL9 | |
| SCHEMBL8330111 | 0.80 | MEN1 (0.51) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP2C19 | |
| SCHEMBL16695904 | 0.80 | HTR2A (0.56) | HTR2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14437515 | 0.80 | HTR2A (0.66) | HTR2ARAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4644851 | 0.80 | HTR2A (0.56) | HTR2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27189134 | 0.80 | HTR2A (0.59) | HTR2ANPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216125-A | Active ester used for production of acylated amino acids | SANSHIN KAGAKU KOGYO CO. LTD. (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5117031-A | ACTIVE ESTERS USED FOR PRODUCTION OF ESTERS OR AMIDES AND PROCESS FOR PRODUCING ESTERS OR AMIDES | SANSHIN KAGAKU KOGYO CO. LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0245662-B1 | P-HYDROXYPHENYLSULFONIUM SALTS AND THEIR USE IN THE PREPARATION OF ESTERS AND AMIDES | SANSHIN KAGAKU KOGYO CO., LTD. (JP) | 1991-08-07 | — | — | EP | disclosed |
| EP-0331988-A1 | Sulfonium compounds, as well as process for producing active esters and amides used for the production of amides | SANSHIN KAGAKU KOGYO CO., LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |
| US-4857656-A | Active esters used for production of esters or amides and process for producing esters or amides | SANSHIN KAGAKU KOGYO CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0245662-A1 | p-Hydroxyphenylsulfonium salts and their use in the preparation of esters and amides | SANSHIN KAGAKU KOGYO CO., LTD. (JP) | 1987-11-19 | — | — | EP | disclosed |
| US-4453003-A | ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS | UMEZAWA HAMAO (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4391986-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediates therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1983-07-05 | — | — | US | disclosed |
| US-4281180-A | Process for producing threo-3-amino-2-hydroxybutanoyl-aminoacetic acids, as well as novel intermediated therefor and process for producing them | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1981-07-28 | — | — | US | disclosed |