Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.44 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7165590 | 0.82 | TSHR (0.42) | TSHRNPSR1LMNAKDM4ECYP2C19 | |
| 2-Pyrrolidone SCHEMBL10474577 | 0.71 | — | — | |
| 2-Pyrrolidone SCHEMBL5832885 | 0.69 | OR51E2 (0.75) | OR51E2FKBP5CRBNTSHRLMNA | |
| 2-Pyrrolidone SCHEMBL3225022 | 0.69 | OR51E2 (0.75) | OR51E2FKBP5CRBNTSHRLMNA | |
| SCHEMBL10358481 | 0.69 | TSHR (0.31) | TSHRNPSR1 | |
| 2-Pyrrolidone SCHEMBL28122178 | 0.69 | — | — | |
| 2-Pyrrolidone SCHEMBL5051625 | 0.67 | — | — | |
| 2-Pyrrolidone SCHEMBL29033368 | 0.67 | — | — | |
| 2-Pyrrolidone SCHEMBL28218276 | 0.67 | — | — | |
| 2-Pyrrolidone SCHEMBL28109610 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776959-A | Anticonvulsant and anxiolytic lactam and thiolactam derivatives | WASHINGTON UNIVERSITY (US) | 1998-07-07 | — | — | US | disclosed |