Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7165590 | 0.83 | TSHR (0.42) | TSHRNPSR1 | |
| SCHEMBL10358028 | 0.77 | — | — | |
| SCHEMBL4975729 | 0.72 | — | — | |
| 2-Pyrrolidone SCHEMBL7440577 | 0.69 | OR51E2 (0.44) | TSHRNPSR1 | |
| SCHEMBL9139804 | 0.68 | — | — | |
| SCHEMBL14119928 | 0.68 | SIRT2 (0.39) | TSHR | |
| SCHEMBL10735776 | 0.65 | — | — | |
| SCHEMBL12109835 | 0.65 | LMNA (0.35) | — | |
| SCHEMBL12109836 | 0.65 | CTSK (0.33) | — | |
| SCHEMBL5858279 | 0.64 | GABRP (0.37) | TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0229007-B1 | ANTICONVULSANT GAMMA-THIOBUTYROLACTONE DERIVATIVES | WASHINGTON UNIVERSITY (US) | 1990-11-28 | — | — | EP | disclosed |
| US-4707491-A | Anticonvulsant γ-thiobutyrolactone derivatives | WASHINGTON UNIVERSITY (US) | 1987-11-17 | — | — | US | disclosed |
| EP-0229007-A1 | Anticonvulsant gamma-thiobutyrolactone derivatives | WASHINGTON UNIVERSITY (US) | 1987-07-15 | — | — | EP | disclosed |